Identification of a negative feedback loop in biological oxidant formation fegulated by 4-hydroxy-2-(E)-nonenal

4-Hydroxy-2-(E)-nonenal (4-HNE) is one of the major lipid peroxidation product formed during oxidative stress. At high concentrations, 4-HNE is cytotoxic and exerts deleterious effects that are often associated with the pathology of oxidative stress-driven disease. Alternatively, at low concentratio...

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Bibliographic Details
Main Authors: Gatbonton-Schwager, Tonibelle N., Sadhukhan, Sushabhan, Zhang, Guo-Fang, Letterio, John J., Tochtrop, Gregory P.
Format: Artigo
Language:Inglês
Published: Elsevier 2014
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085345/
https://ncbi.nlm.nih.gov/pubmed/25009777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2014.04.009
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