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Human Eukaryotic Initiation Factor 2 (eIF2)-GTP-Met-tRNA(i) Ternary Complex and eIF3 Stabilize the 43 S Preinitiation Complex
The formation of a stable 43 S preinitiation complex (PIC) must occur to enable successful mRNA recruitment. However, the contributions of eIF1, eIF1A, eIF3, and the eIF2-GTP-Met-tRNA(i) ternary complex (TC) in stabilizing the 43 S PIC are poorly defined. We have reconstituted the human 43 S PIC and...
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| Veröffentlicht in: | J Biol Chem |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4231660/ https://ncbi.nlm.nih.gov/pubmed/25246524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.602870 |
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