NIAM-Deficient Mice Are Predisposed to the Development of Proliferative Lesions including B-Cell Lymphomas

Nuclear Interactor of ARF and Mdm2 (NIAM, gene designation Tbrg1) is a largely unstudied inhibitor of cell proliferation that helps maintain chromosomal stability. It is a novel activator of the ARF-Mdm2-Tip60-p53 tumor suppressor pathway as well as other undefined pathways important for genome main...

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Udgivet i:PLoS One
Main Authors: Reed, Sara M., Hagen, Jussara, Muniz, Viviane P., Rosean, Timothy R., Borcherding, Nick, Sciegienka, Sebastian, Goeken, J. Adam, Naumann, Paul W., Zhang, Weizhou, Tompkins, Van S., Janz, Siegfried, Meyerholz, David K., Quelle, Dawn E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231569/
https://ncbi.nlm.nih.gov/pubmed/25393878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112126
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