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Residues in the Alternative Reading Frame Tumor Suppressor that Influence its Stability and p53-Independent Activities
The Alternative Reading Frame (ARF) protein suppresses tumorigenesis through p53-dependent and p53-independent pathways. Most of ARF’s anti-proliferative activity is conferred by sequences in its first exon. Previous work showed specific amino acid changes occurred in that region during primate evol...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665200/ https://ncbi.nlm.nih.gov/pubmed/19331830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.01.010 |
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