Residues in the Alternative Reading Frame Tumor Suppressor that Influence its Stability and p53-Independent Activities

The Alternative Reading Frame (ARF) protein suppresses tumorigenesis through p53-dependent and p53-independent pathways. Most of ARF’s anti-proliferative activity is conferred by sequences in its first exon. Previous work showed specific amino acid changes occurred in that region during primate evol...

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Bibliographic Details
Main Authors: di Tommaso, Anne, Hagen, Jussara, Tompkins, Van, Muniz, Viviane, Dudakovic, Amel, Kitzis, Alain, Ladeveze, Veronique, Quelle, Dawn E.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665200/
https://ncbi.nlm.nih.gov/pubmed/19331830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.01.010
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