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Hidden Disease Susceptibility and Sexual Dimorphism in the Heterozygous Knockout of Cyp51 from Cholesterol Synthesis
We examined the genotype-phenotype interactions of Cyp51(+/−) mice carrying one functional allele of lanosterol 14α-demethylase from cholesterol biosynthesis. No distinct developmental or morphological abnormalities were observed by routine visual inspection of Cyp51(+/−) and Cyp51(+/+) mice and fer...
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| Izdano u: | PLoS One |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4231084/ https://ncbi.nlm.nih.gov/pubmed/25393872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112787 |
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