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Transferrin-antibody fusion proteins are effective in brain targeting.

In the present study, the receptor binding potential of transferrin (Tf) was linked to an antibody binding specificity. Human Tf was fused to mouse-human chimeric IgG3 at three positions: at the end of heavy chain constant region 1 (CH1), after the hinge, and after CH3. The resulting Tf-antibody fus...

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Bibliografski detalji
Glavni autori: Shin, S U, Friden, P, Moran, M, Olson, T, Kang, Y S, Pardridge, W M, Morrison, S L
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC42310/
https://ncbi.nlm.nih.gov/pubmed/7708731
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