ロード中...
Pharmacokinetics and Brain Uptake of a Genetically Engineered Bi-functional Fusion Antibody Targeting the Mouse Transferrin Receptor
Monoclonal antibodies (MAb) are potential new therapeutics for brain diseases. However, MAb’s do not cross the blood-brain barrier (BBB). The present work describes the genetic engineering of a fusion protein comprised of a therapeutic single chain Fv (ScFv) antibody and a mouse/rat chimeric MAb aga...
保存先:
| 主要な著者: | , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
|
| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858389/ https://ncbi.nlm.nih.gov/pubmed/19921848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900235k |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|