A Brain Penetrating Bifunctional Erythropoietin-Transferrin Receptor Antibody Fusion Protein for Alzheimer’s Disease

OBJECTIVE: Erythropoietin (EPO), a glycoprotein cytokine essential to hematopoiesis, has neuroprotective effects in rodent models of Alzheimer’s disease (AD). However, high therapeutic doses or invasive routes of administration of EPO are required to achieve effective brain concentrations due to low...

詳細記述

保存先:
書誌詳細
出版年:Mol Pharm
主要な著者: Chang, Rudy, Maghribi, Abrar Al, Vanderpoel, Victoria, Vasilevko, Vitaly, Cribbs, David H., Boado, Ruben, Pardridge, William M., Sumbria, Rachita K.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457666/
https://ncbi.nlm.nih.gov/pubmed/30252487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b00594
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料