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Transferrin-antibody fusion proteins are effective in brain targeting.

In the present study, the receptor binding potential of transferrin (Tf) was linked to an antibody binding specificity. Human Tf was fused to mouse-human chimeric IgG3 at three positions: at the end of heavy chain constant region 1 (CH1), after the hinge, and after CH3. The resulting Tf-antibody fus...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Shin, S U, Friden, P, Moran, M, Olson, T, Kang, Y S, Pardridge, W M, Morrison, S L
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1995
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC42310/
https://ncbi.nlm.nih.gov/pubmed/7708731
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