A well-differentiated B-cell line is permissive for somatic mutation of a transfected immunoglobulin heavy-chain gene.

pSV2neo plasmids containing an IgM heavy-chain gene with nonsense mutations in either the variable (V) or the constant (C) region were transfected into four differentiated mouse plasma cell lines: S107 and the NSO fusion partner (myeloma cell lines) and 2C3 and 36.65 (hybridoma cell lines). The freq...

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Argitaratua izan da:	Proc Natl Acad Sci U S A
Egile Nagusiak:	Zhu, M, Rabinowitz, J L, Green, N S, Kobrin, B J, Scharff, M D
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	National Academy of Sciences 1995
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42308/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7708729/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2810
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