Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors

The conversion of somatic cells into pluripotent stem cells via overexpression of reprogramming factors involves epigenetic remodeling. DNA methylation at a significant proportion of CpG sites in induced pluripotent stem cells (iPSCs) differs from that of embryonic stem cells (ESCs). Whether differe...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Regen
Asıl Yazarlar: Planello, Aline C, Ji, Junfeng, Sharma, Vivek, Singhania, Rajat, Mbabaali, Faridah, Müller, Fabian, Alfaro, Javier A, Bock, Christoph, De Carvalho, Daniel D, Batada, Nizar N
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230737/
https://ncbi.nlm.nih.gov/pubmed/25408883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-9769-3-4
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