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OCT4: A penetrant pluripotency inducer

Native OCT4 protein has the intrinsic ability of crossing cellular membranes to enter cells. This finding could revive efforts to induce pluripotency with proteins replacing nucleic acid-based approaches, and raises the intriguing question as to whether OCT4 can act non-cell-autonomously.

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Bibliografiske detaljer
Udgivet i:Cell Regen
Main Authors: Wang, Xuecong, Jauch, Ralf
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230516/
https://ncbi.nlm.nih.gov/pubmed/25408885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-9769-3-6
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