The role of high cell density in the promotion of neuroendocrine transdifferentiation of prostate cancer cells

BACKGROUND: Tumor heterogeneity and the plasticity of cancer cells present challenges for effective clinical diagnosis and therapy. Such challenges are epitomized by neuroendocrine transdifferentiation (NED) and the emergence of neuroendocrine-like cancer cells in prostate tumors. This phenomenon fr...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Pernicová, Zuzana, Slabáková, Eva, Fedr, Radek, Šimečková, Šárka, Jaroš, Josef, Suchánková, Tereza, Bouchal, Jan, Kharaishvili, Gvantsa, Král, Milan, Kozubík, Alois, Souček, Karel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229954/
https://ncbi.nlm.nih.gov/pubmed/24884804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-113
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