A new sensitive PCR assay for one-step detection of 12 IDH1/2 mutations in glioma

INTRODUCTION: Mutations in isocitrate dehydrogenase genes IDH1 or IDH2 are frequent in glioma, and IDH mutation status is a strong diagnostic and prognostic marker. Current IDH mutation screening is performed with an immunohistochemistry (IHC) assay specific for IDH1 R132H, the most common mutation....

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Catteau, Aurélie, Girardi, Hélène, Monville, Florence, Poggionovo, Cécile, Carpentier, Sabrina, Frayssinet, Véronique, Voss, Jesse, Jenkins, Robert, Boisselier, Blandine, Mokhtari, Karima, Sanson, Marc, Peyro-Saint-Paul, Hélène, Giannini, Caterina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229941/
https://ncbi.nlm.nih.gov/pubmed/24889502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-58
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