IDH Mutations: Genotype-Phenotype Correlation and Prognostic Impact

IDH1/2 mutation is the most frequent genomic alteration found in gliomas, affecting 40% of these tumors and is one of the earliest alterations occurring in gliomagenesis. We investigated a series of 1305 gliomas and showed that IDH mutation is almost constant in 1p19q codeleted tumors. We found that...

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Detalhes bibliográficos
Main Authors: Wang, Xiao-Wei, Ciccarino, Pietro, Rossetto, Marta, Boisselier, Blandine, Marie, Yannick, Desestret, Virginie, Gleize, Vincent, Mokhtari, Karima, Sanson, Marc, Labussière, Marianne
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022066/
https://ncbi.nlm.nih.gov/pubmed/24877111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/540236
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