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Oxidative stress increases pulmonary vascular permeability in diabetic rats through activation of transient receptor potential melastatin 2 (TRPM2) channels
OBJECTIVE: In vitro superoxide activates pulmonary endothelial TRPM2 channels and increases the capillary filtration coefficient (Kf). We hypothesized that pulmonary capillary Kf is increased in a model of type I diabetes due to elevated vascular superoxide and resultant TRPM2 channel activation. ME...
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| Publicado no: | Microcirculation |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4229396/ https://ncbi.nlm.nih.gov/pubmed/25059284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12158 |
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