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Oxidative stress contributes to orthopedic trauma-induced acute kidney injury in obese rats
After trauma, obese patients have an increased risk of developing acute kidney injury (AKI). We have demonstrated that obese Zucker (OZ) rats, but not lean Zucker (LZ) rats, develop AKI 24 h after orthopedic trauma. ROS have been implicated in the pathophysiology of AKI in models of critical illness...
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| Veröffentlicht in: | Am J Physiol Renal Physiol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4338927/ https://ncbi.nlm.nih.gov/pubmed/25428128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00537.2014 |
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