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Oxidative stress contributes to orthopedic trauma-induced acute kidney injury in obese rats

After trauma, obese patients have an increased risk of developing acute kidney injury (AKI). We have demonstrated that obese Zucker (OZ) rats, but not lean Zucker (LZ) rats, develop AKI 24 h after orthopedic trauma. ROS have been implicated in the pathophysiology of AKI in models of critical illness...

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Vydáno v:Am J Physiol Renal Physiol
Hlavní autoři: Mittwede, Peter N., Xiang, Lusha, Lu, Silu, Clemmer, John S., Hester, Robert L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338927/
https://ncbi.nlm.nih.gov/pubmed/25428128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00537.2014
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