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Oxidative stress contributes to orthopedic trauma-induced acute kidney injury in obese rats

After trauma, obese patients have an increased risk of developing acute kidney injury (AKI). We have demonstrated that obese Zucker (OZ) rats, but not lean Zucker (LZ) rats, develop AKI 24 h after orthopedic trauma. ROS have been implicated in the pathophysiology of AKI in models of critical illness...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Mittwede, Peter N., Xiang, Lusha, Lu, Silu, Clemmer, John S., Hester, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338927/
https://ncbi.nlm.nih.gov/pubmed/25428128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00537.2014
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