The Actin Targeting Compound Chondramide Inhibits Breast Cancer Metastasis via Reduction of Cellular Contractility

BACKGROUND: A major player in the process of metastasis is the actin cytoskeleton as it forms key structures in both invasion mechanisms, mesenchymal and amoeboid migration. We tested the actin binding compound Chondramide as potential anti-metastatic agent. METHODS: In vivo, the effect of Chondrami...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Menhofer, Magdalena H., Kubisch, Rebekka, Schreiner, Laura, Zorn, Matthias, Foerster, Florian, Mueller, Rolf, Raedler, Joachim O., Wagner, Ernst, Vollmar, Angelika M., Zahler, Stefan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229209/
https://ncbi.nlm.nih.gov/pubmed/25391145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112542
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