The Actin Targeting Compound Chondramide Inhibits Breast Cancer Metastasis via Reduction of Cellular Contractility

BACKGROUND: A major player in the process of metastasis is the actin cytoskeleton as it forms key structures in both invasion mechanisms, mesenchymal and amoeboid migration. We tested the actin binding compound Chondramide as potential anti-metastatic agent. METHODS: In vivo, the effect of Chondrami...

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Publicat a:PLoS One
Autors principals: Menhofer, Magdalena H., Kubisch, Rebekka, Schreiner, Laura, Zorn, Matthias, Foerster, Florian, Mueller, Rolf, Raedler, Joachim O., Wagner, Ernst, Vollmar, Angelika M., Zahler, Stefan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229209/
https://ncbi.nlm.nih.gov/pubmed/25391145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112542
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