The Actin Targeting Compound Chondramide Inhibits Breast Cancer Metastasis via Reduction of Cellular Contractility

BACKGROUND: A major player in the process of metastasis is the actin cytoskeleton as it forms key structures in both invasion mechanisms, mesenchymal and amoeboid migration. We tested the actin binding compound Chondramide as potential anti-metastatic agent. METHODS: In vivo, the effect of Chondrami...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Menhofer, Magdalena H., Kubisch, Rebekka, Schreiner, Laura, Zorn, Matthias, Foerster, Florian, Mueller, Rolf, Raedler, Joachim O., Wagner, Ernst, Vollmar, Angelika M., Zahler, Stefan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229209/
https://ncbi.nlm.nih.gov/pubmed/25391145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112542
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares