RAE-1 ligands for the NKG2D receptor are regulated by STING-dependent DNA sensor pathways in lymphoma

The immunoreceptor NKG2D originally identified in natural killer cells recognizes ligands that are upregulated on tumor cells. Expression of NKG2D ligands (NKG2DLs) is activated by the DNA damage response (DDR) which is often activated constitutively in cancer cells, revealing them to natural killer...

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Vydáno v:Cancer Res
Hlavní autoři: Lam, Adeline R, Bert, Nina Le, Ho, Samantha SW, Shen, Yu J, Tang, Li FM, Xiong, Gordon M, Croxford, John L, Koo, Christine X, Ishii, Ken J, Akira, Shizuo, Raulet, David H, Gasser, Stephan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229084/
https://ncbi.nlm.nih.gov/pubmed/24590060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1703
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