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STING-dependent cytosolic DNA sensor pathways regulate NKG2D ligand expression

The DNA damage response (DDR) upregulates the expression of NKG2D ligands (NKG2DLs).(1,2) We have recently reported that the DDR also induces the presence of cytosolic DNA in B-cell lymphoma cells, which leads to the activation of STING-dependent cytosolic DNA sensor pathways and the expression of R...

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Bibliografiske detaljer
Main Authors: Le Bert, Nina, Lam, Adeline R, Ho, Samantha SW, Shen, Yu J, Liu, Mo M, Gasser, Stephan
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126837/
https://ncbi.nlm.nih.gov/pubmed/25114832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.29259
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