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STING-dependent cytosolic DNA sensor pathways regulate NKG2D ligand expression

The DNA damage response (DDR) upregulates the expression of NKG2D ligands (NKG2DLs).(1,2) We have recently reported that the DDR also induces the presence of cytosolic DNA in B-cell lymphoma cells, which leads to the activation of STING-dependent cytosolic DNA sensor pathways and the expression of R...

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Bibliografski detalji
Glavni autori: Le Bert, Nina, Lam, Adeline R, Ho, Samantha SW, Shen, Yu J, Liu, Mo M, Gasser, Stephan
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126837/
https://ncbi.nlm.nih.gov/pubmed/25114832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.29259
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