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STING-dependent cytosolic DNA sensor pathways regulate NKG2D ligand expression

The DNA damage response (DDR) upregulates the expression of NKG2D ligands (NKG2DLs).(1,2) We have recently reported that the DDR also induces the presence of cytosolic DNA in B-cell lymphoma cells, which leads to the activation of STING-dependent cytosolic DNA sensor pathways and the expression of R...

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Main Authors: Le Bert, Nina, Lam, Adeline R, Ho, Samantha SW, Shen, Yu J, Liu, Mo M, Gasser, Stephan
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126837/
https://ncbi.nlm.nih.gov/pubmed/25114832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.29259
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