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STING-dependent cytosolic DNA sensor pathways regulate NKG2D ligand expression

The DNA damage response (DDR) upregulates the expression of NKG2D ligands (NKG2DLs).(1,2) We have recently reported that the DDR also induces the presence of cytosolic DNA in B-cell lymphoma cells, which leads to the activation of STING-dependent cytosolic DNA sensor pathways and the expression of R...

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Detalhes bibliográficos
Main Authors: Le Bert, Nina, Lam, Adeline R, Ho, Samantha SW, Shen, Yu J, Liu, Mo M, Gasser, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126837/
https://ncbi.nlm.nih.gov/pubmed/25114832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.29259
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