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The DNA damage pathway regulates innate immune system ligands for the NKG2D receptor

Some stimulatory receptors of the innate immune system, such as the NKG2D receptor expressed by NK cells and activated CD8(+) T cells, recognize self-molecules that are upregulated in diseased cells by poorly understood mechanisms1. Here we show that mouse and human NKG2D ligands are upregulated in...

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Détails bibliographiques
Auteurs principaux: Gasser, Stephan, Orsulic, Sandra, Brown, Eric J., Raulet, David H.
Format: Artigo
Langue:Inglês
Publié: 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1352168/
https://ncbi.nlm.nih.gov/pubmed/15995699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03884
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