Učitavanje...
Unlocking a Caged Lysosomal Protein from a Polymeric Nanogel with a pH Trigger
[Image: see text] A polymeric nanogel has been used to sequester and turn off a lysosomal protein, acid α-glucosidase (GAA). The nanogel contains a β-thiopropionate cross-linker, which endows the nanogel with pH-sensitivity. While encapsulation of the enzyme fully turns off its activity, approximate...
Spremljeno u:
| Izdano u: | Biomacromolecules |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical Society
2014
|
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4229022/ https://ncbi.nlm.nih.gov/pubmed/25291086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm501091p |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|