Načítá se...
Unlocking a Caged Lysosomal Protein from a Polymeric Nanogel with a pH Trigger
[Image: see text] A polymeric nanogel has been used to sequester and turn off a lysosomal protein, acid α-glucosidase (GAA). The nanogel contains a β-thiopropionate cross-linker, which endows the nanogel with pH-sensitivity. While encapsulation of the enzyme fully turns off its activity, approximate...
Uloženo v:
| Vydáno v: | Biomacromolecules |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Chemical Society
2014
|
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4229022/ https://ncbi.nlm.nih.gov/pubmed/25291086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm501091p |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|