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Targeting proteins for degradation

Protein degradation plays a central role in many cellular functions. Misfolded and damaged proteins are removed from the cell to avoid toxicity. The concentrations of regulatory proteins are adjusted by degradation at the appropriate time. Both foreign and native proteins are digested into small pep...

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Dades bibliogràfiques
Publicat a:Nat Chem Biol
Autors principals: Schrader, Erin K, Harstad, Kristine G, Matouschek, Andreas
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228941/
https://ncbi.nlm.nih.gov/pubmed/19841631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.250
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