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Targeting proteins for degradation
Protein degradation plays a central role in many cellular functions. Misfolded and damaged proteins are removed from the cell to avoid toxicity. The concentrations of regulatory proteins are adjusted by degradation at the appropriate time. Both foreign and native proteins are digested into small pep...
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| Publié dans: | Nat Chem Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4228941/ https://ncbi.nlm.nih.gov/pubmed/19841631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.250 |
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