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Targeting proteins for degradation

Protein degradation plays a central role in many cellular functions. Misfolded and damaged proteins are removed from the cell to avoid toxicity. The concentrations of regulatory proteins are adjusted by degradation at the appropriate time. Both foreign and native proteins are digested into small pep...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Chem Biol
Main Authors: Schrader, Erin K, Harstad, Kristine G, Matouschek, Andreas
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228941/
https://ncbi.nlm.nih.gov/pubmed/19841631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.250
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