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Targeting proteins for degradation

Protein degradation plays a central role in many cellular functions. Misfolded and damaged proteins are removed from the cell to avoid toxicity. The concentrations of regulatory proteins are adjusted by degradation at the appropriate time. Both foreign and native proteins are digested into small pep...

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Bibliografische gegevens
Gepubliceerd in:Nat Chem Biol
Hoofdauteurs: Schrader, Erin K, Harstad, Kristine G, Matouschek, Andreas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228941/
https://ncbi.nlm.nih.gov/pubmed/19841631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.250
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