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Dye label interference with RNA modification reveals 5-fluorouridine as non-covalent inhibitor
The interest in RNA modification enzymes surges due to their involvement in epigenetic phenomena. Here we present a particularly informative approach to investigate the interaction of dye-labeled RNA with modification enzymes. We investigated pseudouridine (Ψ) synthase TruB interacting with an alleg...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4227767/ https://ncbi.nlm.nih.gov/pubmed/25300485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku908 |
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