Absolute and relative quantification of RNA modifications via biosynthetic isotopomers

In the resurging field of RNA modifications, quantification is a bottleneck blocking many exciting avenues. With currently over 150 known nucleoside alterations, detection and quantification methods must encompass multiple modifications for a comprehensive profile. LC–MS/MS approaches offer a perspe...

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Detalhes bibliográficos
Main Authors: Kellner, Stefanie, Ochel, Antonia, Thüring, Kathrin, Spenkuch, Felix, Neumann, Jennifer, Sharma, Sunny, Entian, Karl-Dieter, Schneider, Dirk, Helm, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191383/
https://ncbi.nlm.nih.gov/pubmed/25129236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku733
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