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Partial Methylation at Am100 in 18S rRNA of Baker's Yeast Reveals Ribosome Heterogeneity on the Level of Eukaryotic rRNA Modification

Ribosome heterogeneity is of increasing biological significance and several examples have been described for multicellular and single cells organisms. In here we show for the first time a variation in ribose methylation within the 18S rRNA of Saccharomyces cerevisiae. Using RNA-cleaving DNAzymes, we...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Buchhaupt, Markus, Sharma, Sunny, Kellner, Stefanie, Oswald, Stefanie, Paetzold, Melanie, Peifer, Christian, Watzinger, Peter, Schrader, Jens, Helm, Mark, Entian, Karl-Dieter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938493/
https://ncbi.nlm.nih.gov/pubmed/24586927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089640
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