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Tumor Suppression by the Fbw7 Ubiquitin Ligase: Mechanisms and Opportunities
Tumor suppressors with widespread impact on carcinogenesis control broad spectra of oncogenic pathways. Protein degradation is an emerging mechanism by which tumor suppressors regulate a diversity of pathways and is exemplified by the SCF(Fbw7) ubiquitin ligase. Rapidly accumulating data indicate th...
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| 出版年: | Cancer Cell |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4227608/ https://ncbi.nlm.nih.gov/pubmed/25314076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2014.09.013 |
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