Nalaganje...
A Cyclin T1 point mutation that abolishes positive transcription elongation factor (P-TEFb) binding to Hexim1 and HIV tat
BACKGROUND: The positive transcription elongation factor b (P-TEFb) plays an essential role in activating HIV genome transcription. It is recruited to the HIV LTR promoter through an interaction between the Tat viral protein and its Cyclin T1 subunit. P-TEFb activity is inhibited by direct binding o...
Shranjeno v:
izdano v: | Retrovirology |
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Main Authors: | , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
BioMed Central
2014
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4227133/ https://ncbi.nlm.nih.gov/pubmed/24985203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-11-50 |
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