Inhibition of Tat activity by the HEXIM1 protein

BACKGROUND: The positive transcription elongation factor b (P-TEFb) composed by CDK9/CyclinT1 subunits is a dedicated co-factor of HIV transcriptional transactivator Tat protein. Transcription driven by the long terminal repeat (LTR) of HIV involves formation of a quaternary complex between P-TEFb,...

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Bibliographic Details
Main Authors: Fraldi, Alessandro, Varrone, Francesca, Napolitano, Giuliana, Michels, Annemieke A, Majello, Barbara, Bensaude, Olivier, Lania, Luigi
Format: Artigo
Language:Inglês
Published: BioMed Central 2005
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1183248/
https://ncbi.nlm.nih.gov/pubmed/15992410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-2-42
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