The PIM family of oncoproteins: Small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets

PIM kinases are a family of serine/threonine kinases involved in cell survival and proliferation. There is significant structural similarity between the three PIM kinases (PIM1, PIM2 and PIM3) and few amino acid differences. Although, several studies have specifically monitored the role of PIM1 in t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Saurabh, Kumar, Scherzer, Michael T., Shah, Parag P., Mims, Alice S., Lockwood, William W., Kraft, Andrew S., Beverly, Levi J.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2014
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226700/
https://ncbi.nlm.nih.gov/pubmed/25238262
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