The PIM family of oncoproteins: Small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets

PIM kinases are a family of serine/threonine kinases involved in cell survival and proliferation. There is significant structural similarity between the three PIM kinases (PIM1, PIM2 and PIM3) and few amino acid differences. Although, several studies have specifically monitored the role of PIM1 in t...

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Udgivet i:Oncotarget
Main Authors: Saurabh, Kumar, Scherzer, Michael T., Shah, Parag P., Mims, Alice S., Lockwood, William W., Kraft, Andrew S., Beverly, Levi J.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226700/
https://ncbi.nlm.nih.gov/pubmed/25238262
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