The PIM family of oncoproteins: Small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets

PIM kinases are a family of serine/threonine kinases involved in cell survival and proliferation. There is significant structural similarity between the three PIM kinases (PIM1, PIM2 and PIM3) and few amino acid differences. Although, several studies have specifically monitored the role of PIM1 in t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Saurabh, Kumar, Scherzer, Michael T., Shah, Parag P., Mims, Alice S., Lockwood, William W., Kraft, Andrew S., Beverly, Levi J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226700/
https://ncbi.nlm.nih.gov/pubmed/25238262
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