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Prospective Development of Small Molecule Targets to Oncogenic Ras Proteins

Abnormal expression or mutations in Ras proteins has been found in up to 30% of cancer cell types, making them excellent protein models to probe structure-function relationships of cell-signaling processes that mediate cell transformtion. Yet, there has been very little development of therapies to h...

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Publicat a:Open J Biophys
Autors principals: Chandrashekar, Reena, Adams, Paul D.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226270/
https://ncbi.nlm.nih.gov/pubmed/25392746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4236/ojbiphy.2013.34025
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