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Targeting the RAS oncogene
INTRODUCTION: The Ras proteins (K-Ras, N-Ras, H-Ras) are GTPases that function as molecular switches for a variety of critical cellular activities and their function is tightly and temporally regulated in normal cells. Oncogenic mutations in the RAS genes, which create constitutively-active Ras prot...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3804031/ https://ncbi.nlm.nih.gov/pubmed/23360111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2013.764990 |
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