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Targeting oncogenic Ras signaling in hematologic malignancies
Ras proteins are critical nodes in cellular signaling that integrate inputs from activated cell surface receptors and other stimuli to modulate cell fate through a complex network of effector pathways. Oncogenic RAS mutations are found in ∼ 25% of human cancers and are highly prevalent in hematopoie...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Hematology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3482854/ https://ncbi.nlm.nih.gov/pubmed/22898602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-378596 |
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