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Targeting oncogenic Ras signaling in hematologic malignancies

Ras proteins are critical nodes in cellular signaling that integrate inputs from activated cell surface receptors and other stimuli to modulate cell fate through a complex network of effector pathways. Oncogenic RAS mutations are found in ∼ 25% of human cancers and are highly prevalent in hematopoie...

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Bibliografski detalji
Glavni autori: Ward, Ashley F., Braun, Benjamin S., Shannon, Kevin M.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482854/
https://ncbi.nlm.nih.gov/pubmed/22898602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-378596
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