An Aberrant Leukotriene A(4) Hydrolase–Proline-Glycine-Proline Pathway in the Pathogenesis of Chronic Obstructive Pulmonary Disease

Rationale: Chronic neutrophilic inflammation is a hallmark in the pathogenesis of chronic obstructive pulmonary disease (COPD) and persists after cigarette smoking has stopped. Mechanisms involved in this ongoing inflammatory response have not been delineated. Objectives: We investigated changes to...

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Veröffentlicht in:Am J Respir Crit Care Med
Hauptverfasser: Wells, J. Michael, O’Reilly, Philip J., Szul, Tomasz, Sullivan, Daniel I., Handley, Guy, Garrett, Chris, McNicholas, Carmel M., Roda, Mojtaba Abdul, Miller, Bruce E., Tal-Singer, Ruth, Gaggar, Amit, Rennard, Stephen I., Jackson, Patricia L., Blalock, J. Edwin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226028/
https://ncbi.nlm.nih.gov/pubmed/24874071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201401-0145OC
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