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Unravelling the structural and mechanistic basis of CRISPR–Cas systems

Bacteria and archaea have evolved sophisticated adaptive immune systems, known as CRISPR–Cas (clustered regularly interspaced short palindromic repeats–CRISPR-associated proteins) systems, which target and inactivate invading viruses and plasmids. Immunity is acquired by integrating short fragments...

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Bibliografische gegevens
Gepubliceerd in:Nat Rev Microbiol
Hoofdauteurs: van der Oost, John, Westra, Edze R., Jackson, Ryan N., Wiedenheft, Blake
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225775/
https://ncbi.nlm.nih.gov/pubmed/24909109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrmicro3279
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