The Wilms' Tumor Gene WT1 − 17AA/− KTS Splice Variant Increases Tumorigenic Activity Through Up-Regulation of Vascular Endothelial Growth Factor in an In Vivo Ovarian Cancer Model

The Wilms' tumor 1 gene WT1 encodes a zinc transcription factor involved in a variety of cancer-related processes. In this study, we sought to investigate the effects of WT1 splice variants on tumorigenic activity and survival in an in vivo ovarian cancer model. To this end, we established stab...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Yamanouchi, Keiko, Ohta, Tsuyoshi, Liu, Zhiyang, Oji, Yusuke, Sugiyama, Haruo, Shridhar, Viji, Matsumura, Sohei, Takahashi, Toshifumi, Takahashi, Kazuhiro, Kurachi, Hirohisa
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225694/
https://ncbi.nlm.nih.gov/pubmed/25389453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2014.07.008
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