Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression

The Wilms' tumor gene WT1 is overexpressed in leukemias and various types of solid tumors, and the WT1 protein was demonstrated to be an attractive target antigen for immunotherapy against these malignancies. Here, we report the outcome of a phase I clinical study of WT1 peptide-based immunothe...

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Detalhes bibliográficos
Main Authors: Oka, Yoshihiro, Tsuboi, Akihiro, Taguchi, Tetsuya, Osaki, Tadashi, Kyo, Taiichi, Nakajima, Hiroko, Elisseeva, Olga A., Oji, Yusuke, Kawakami, Manabu, Ikegame, Kazuhiro, Hosen, Naoki, Yoshihara, Satoshi, Wu, Fei, Fujiki, Fumihiro, Murakami, Masaki, Masuda, Tomoki, Nishida, Sumiyuki, Shirakata, Toshiaki, Nakatsuka, Shin-ichi, Sasaki, Ayako, Udaka, Keiko, Dohy, Hiroo, Aozasa, Katsuyuki, Noguchi, Shinzaburo, Kawase, Ichiro, Sugiyama, Haruo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC518848/
https://ncbi.nlm.nih.gov/pubmed/15365188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405884101
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