Biased usage of T cell receptor β‐chain variable region genes of Wilms’ tumor gene (WT1)‐specific CD8(+) T cells in patients with solid tumors and healthy donors

Wilms’ tumor gene 1 (WT1) protein is a promising tumor‐associated antigen. In patients with WT1‐expressing malignancies, WT1‐specific CTLs are spontaneously induced as a result of an immune response to the WT1 protein. In the present study, we performed single cell‐level comparative analysis of T ce...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Morimoto, Soyoko, Oka, Yoshihiro, Tsuboi, Akihiro, Tanaka, Yukie, Fujiki, Fumihiro, Nakajima, Hiroko, Hosen, Naoki, Nishida, Sumiyuki, Nakata, Jun, Nakae, Yoshiki, Maruno, Motohiko, Myoui, Akira, Enomoto, Takayuki, Izumoto, Shuichi, Sekimoto, Mitsugu, Kagawa, Naoki, Hashimoto, Naoya, Yoshimine, Toshiki, Oji, Yusuke, Kumanogoh, Atsushi, Sugiyama, Haruo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7713615/
https://ncbi.nlm.nih.gov/pubmed/22126448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2011.02163.x
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