The Rac Inhibitor EHop-016 Inhibits Mammary Tumor Growth and Metastasis in a Nude Mouse Model

Metastatic disease still lacks effective treatments, and remains the primary cause of cancer mortality. Therefore, there is a critical need to develop better strategies to inhibit metastatic cancer. The Rho family GTPase Rac is an ideal target for anti-metastatic cancer therapy, because Rac is a key...

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Publicado en:Transl Oncol
Autores principales: Castillo-Pichardo, Linette, Humphries-Bickley, Tessa, De La Parra, Columba, Forestier-Roman, Ingrid, Martinez-Ferrer, Magaly, Hernandez, Eliud, Vlaar, Cornelis, Ferrer-Acosta, Yancy, Washington, Anthony V., Cubano, Luis A., Rodriguez-Orengo, Jose, Dharmawardhane, Suranganie
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225654/
https://ncbi.nlm.nih.gov/pubmed/25389450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2014.07.004
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