Oxidative stress diverts tRNA synthetase to nucleus for protection against DNA damage

Tyrosyl-tRNA synthetase (TyrRS) is known for its essential aminoacylation function in protein synthesis. Here we report a new function for TyrRS in DNA damage protection. We found that oxidative stress, which often down-regulates protein synthesis, induces TyrRS to rapidly translocate from the cytos...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Cell
Asıl Yazarlar: Wei, Na, Shi, Yi, Truong, Lan N., Fisch, Kathleen M., Xu, Tao, Gardiner, Elisabeth, Fu, Guangsen, Hsu, Yun-Shiuan Olivia, Kishi, Shuji, Su, Andrew I., Wu, Xiaohua, Yang, Xiang-Lei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224670/
https://ncbi.nlm.nih.gov/pubmed/25284223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.09.006
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller