Mutant MMP-9 and HGF Gene Transfer Enhance Resolution of CCl(4)-Induced Liver Fibrosis in Rats: Role of ASH1 and EZH2 Methyltransferases Repression

Hepatocyte growth factor (HGF) gene transfer inhibits liver fibrosis by regulating aberrant cellular functions, while mutant matrix metalloproteinase-9 (mMMP-9) enhances matrix degradation by neutralizing the elevated tissue inhibitor of metalloproteinase-1 (TIMP-1). It was shown that ASH1 and EZH2...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Atta, Hussein, El-Rehany, Mahmoud, Hammam, Olfat, Abdel-Ghany, Hend, Ramzy, Maggie, Roderfeld, Martin, Roeb, Elke, Al-Hendy, Ayman, Raheim, Salama Abdel, Allam, Hatem, Marey, Heba
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224431/
https://ncbi.nlm.nih.gov/pubmed/25380300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112384
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados